Tritium retention in femoral bone marrow and spleens of mice receiving single intravenous injections of tritiated water and tritiated thymidine.
نویسندگان
چکیده
منابع مشابه
Cytological damage produced in the mouse testes by tritiated thymidine, tritiated water and x-rays.
Irradiation of the mouse testes was carried out using internally distributed tritium from injected tritiated thymidine and tritiated water and also using external whole body irradiation with 200 kVp X-rays. The inability of intermediate spermatogonia to divide twice and produce resting primary spermatocytes was used as a criterion of biological damage and the following conclusions were reached:...
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Wistar rats have continuously ingested tritiated food (48.1 kBq/g) or tritiated water (37.0 kBq/ml) from three weeks before mating of P0 through delivery of the F3 generation. An analysis of tissues at various ages during treatment shows that: (1) tritium incorporation into tissues of rats life-time exposed to tritiated food was on the average 3.53=0.38 times higher than after similar exposure ...
متن کاملTritium labeling of antisense oligonucleotides by exchange with tritiated water.
We describe a simple, efficient, procedure for labeling oligonucleotides to high specific activity (< 1 x 10(8) cpm/mumol) by hydrogen exchange with tritiated water at the C8 positions of purines in the presence of beta-mercaptoethanol, an effective radical scavenger. Approximately 90% of the starting material is recovered as intact, labeled oligonucleotide. The radiolabeled compounds are stabl...
متن کاملThe effects of tritiated water on the bone marrow cells in mice.
Tritium RBE/Tritiated Water/CFUs/CFUc The acute effects on hematopoietic tissue in mice of a single administration of tritiated water were compared with the effects of exposure to 6OCo gamma radiation. The activity of tritium in the bone marrow was measured directly using a sample oxidizer and the absorbed dose was calculated from the amount of activity of tritium in it. The number of nucleated...
متن کاملKinetic Parameters of Bone Marrow Stem Cells Using In Vivo Suicide by Tritiated Thymidine
The kinetics of colony-forming units (CFU) ment. A computer model helped to explain of the bone marrow in mice were studied the experimental results. The feedback using a method involving the suicide of mechanism seemed to be initiated by the cells in vivo by 3H-TdR or hydroxyurea. depletion of the compartment of maturing After selectively killing cells in S phase, cells. This hypothesis is sup...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 1987
ISSN: 0449-3060,1349-9157
DOI: 10.1269/jrr.28.204